Ethoxymethylene CAS  87-13-8, also known as ethoxymethylene malonate diethyl ester, is a colorless and transparent viscous liquid. It is an important pharmaceutical intermediate widely used in the synthesis of pharmaceuticals, pesticides, and additives. It is an intermediate for the production of chloroquine, norfloxacin, and lomefloxacin.

Chinese name: Ethoxymethylene

Foreign name: Diethyl Ethoxymethylenemalate

Alias: EMME; Ethoxymethylene malonate diethyl ester; Ethoxymethylene malonate diethyl ester

Chemical formula: C10H16O5

Molecular weight: 216.23

CAS login number: 87-13-8

EINECS login number: 201-725-7

Boiling point: 279-281 ℃

Water solubility: insoluble in water

Density: 1.07 (relative to water)

Appearance: Colorless transparent viscous liquid

Flash point: 155 ℃

Application: Containing various active groups, capable of condensation and cyclization condensation, mainly used for synthesizing norfloxacin.

Purpose

An important organic raw material containing multiple active groups in a molecule, which can undergo condensation and cyclization condensation with various substances. It is widely used in the synthesis of pharmaceuticals, pesticides, and additives, and is an intermediate in the production of chloroquine, norfloxacin, and lomefloxacin.

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