CAS 6055-19-2 Cyclophosphamide monohydrate
Cyclophosphamide monohydrate CAS 6055-19-2 is an organic compound with the chemical formula C7H15O2N2PCl2 · H2O. It is a white crystalline or crystalline powder with a solubility of 40g/L in water, slightly soluble in alcohol, benzene, ethylene glycol, carbon tetrachloride, and dioxane, and almost insoluble in ether and acetone. Losing crystalline water means liquefaction, and the aqueous solution is unstable. No odor, slightly bitter taste. Cyclophosphamide monohydrate is a synthetic DNA Alkylator that is chemically related to nitrogen mustard and has anti-tumor and immunosuppressive activities.
Chinese name: cyclophosphamide monohydrate
Foreign name: cyclophyside hydrate
Cyclophosphamide monohydrate
Nicknames: cyclophosphamide monohydrate, Candexin, 2- [N, N-bis (2-chloroethyl)] -1,3,2-oxynitrophosphate-2-oxide monohydrate, cyclophosphamide, monohydrate, P – [N, N-bis( β- Chloroethyl)] -1-Oxy-3-Nitro-2-Phosphohexane-P-Oxide
Chemical formula: C7H15O2N2PCl2 · H2O
Molecular weight: 279.101
CAS login number: 6055-19-2
EINECS login number: 200-015-4
Melting point: 49 to 51 ℃
Boiling point: 336.1 ℃ (760 mmHg)
Appearance: White crystalline or crystalline powder
Physical and chemical properties
Appearance and properties: White to grayish white solid
Melting point: 49-51 ° C (lit.)
Boiling point: 336.1 º C at 760 mmHg
Water solubility: 40 g/L
Storage conditions: 2-8 º C
Purpose
Antitumor drugs. It is effective for malignant lymphoma and has a certain therapeutic effect on acute lymphoblastic leukemia. It is also effective for chronic lymphoblastic leukemia, breast cancer, ovarian cancer, testicular cancer, multiple myeloma, neuroblastoma, head and neck cancer, and colon cancer. This product still has immunosuppressive effects. Used for nephrotic syndrome and rheumatoid arthritis. The toxicity of this product is 35094mg/kg for oral LD50 in mice.
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