CAS 56-12-2 γ- Aminobutyric acid
γ- Aminobutyric acid CAS 56-12-2 , English name: γ‑ Aminobutyric acid (GABA) γ- Aminobutyric acid, chemical name: 4-aminobutyric acid; Alias: γ- Aminobutyric acid, aminobutyric acid, and pipecolic acid are widely distributed in animals and plants. The seeds, rhizomes, and tissue fluids of plants such as beans, ginseng, and Chinese herbal medicine all contain γ- Aminobutyric acid. In Chemicalbook animals, GABA is almost exclusively present in neural tissue, with a concentration of approximately 0.1-0.6mg/g in brain tissue. Immunological studies have shown that its highest concentration is in the substantia nigra of the brain. γ- Aminobutyric acid is an important inhibitory neurotransmitter that has been extensively studied. It participates in various metabolic activities and has high physiological activity.
γ- Aminobutyric acid (GABA) is a natural active ingredient widely distributed in animals and plants. The seeds, rhizomes, and tissue fluids of plants such as beans, ginseng, and Chinese herbal medicine all contain γ- Aminobutyric acid. In the animal Chemicalbook, γ- Aminobutyric acid is almost exclusively present in neural tissue, with a concentration of approximately 0.1-0.6mg/g in brain tissue. Immunological studies have shown that its highest concentration is in the substantia nigra of the brain.
γ- Aminobutyric acid is a strong neuroinhibitory amino acid that has physiological effects such as sedation, hypnosis, anticonvulsant, and blood pressure lowering. It is an inhibitory neurotransmitter that can inhibit animal activity and reduce energy consumption. Aminobutyric acid acts on animal cells γ- Aminobutyric acid receptor, γ- The aminobutyrate chemicalbook acid receptor is a chloride ion channel, γ- The inhibitory or excitatory properties of aminobutyric acid depend on the concentration of chloride ions inside and outside the cell membrane, γ- After the activation of the aminobutyric acid receptor, it leads to the opening of chloride ion channels, which can increase the permeability of the cell membrane to chloride ions, causing chloride ions to flow into nerve cells, causing hyperpolarization of the cell membrane, inhibiting neuronal activation, and thereby reducing animal movement.
Specification
Melting point 195 ° C
Boiling point 248.0 ± 23.0 ° C
Density 1.2300 (estimate)
Solubility H2O: 1 M at 20 ° C, clear, colorless
Appearance: White to most white powder
Application
Pharmaceutical intermediates. 4-Aminobutyric acid has a lipid-lowering effect and is suitable for the treatment and prevention of various types of liver coma. Treat polio, cerebral hemorrhage, and can be used as an antidote for gas poisoning. It is also used in biochemical research and organic synthesis of Chemicalbooks.
It can reduce blood ammonia and promote brain metabolism. Used to treat various types of liver coma, as well as coma caused by stroke sequelae, cerebral arteriosclerosis, head injury sequelae, uremia, gas poisoning, etc.
Packing
25kg/bag
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